Mesodermal origin of median fin mesenchyme and tail muscle in amphibian larvae

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Mesodermal origin of median fin mesenchyme and tail muscle in amphibian larvae

Mesenchyme is an embryonic precursor tissue that generates a range of structures in vertebrates including cartilage, bone, muscle, kidney, and the erythropoietic system. Mesenchyme originates from both mesoderm and the neural crest, an ectodermal cell population, via an epithelial to mesenchymal transition (EMT). Because ectodermal and mesodermal mesenchyme can form in close proximity and give ...

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An exclusively mesodermal origin of fin mesenchyme demonstrates that zebrafish trunk neural crest does not generate ectomesenchyme.

The neural crest is a multipotent stem cell population that arises from the dorsal aspect of the neural tube and generates both non-ectomesenchymal (melanocytes, peripheral neurons and glia) and ectomesenchymal (skeletogenic, odontogenic, cartilaginous and connective tissue) derivatives. In amniotes, only cranial neural crest generates both classes, with trunk neural crest restricted to non-ect...

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Effects of fin fold mesenchyme ablation on fin development in zebrafish

The evolution of the tetrapod limb involved an expansion and elaboration of the endoskeletal elements, while the fish fin rays were lost. Loss of fin-specific genes, and regulatory changes in key appendicular patterning genes have been identified as mechanisms of limb evolution, however their contributions to cellular organization and tissue differences between fins and limbs remains poorly und...

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Mechanical properties of the tadpole tail fin

The tadpole tail fin is a simple double layer of skin overlying loose connective tissue. Collagen fibres in the fin are oriented at approximately +/-45 degrees from the long axis of the tail. Three tests were conducted on samples of the dorsal tail fin from 6-10 Rana catesbeiana tadpoles to establish the fin's viscoelastic properties under (1) large-deformation cyclic loading at 1 and 3 Hz, (2)...

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Macrophages modulate adult zebrafish tail fin regeneration

Neutrophils and macrophages, as key mediators of inflammation, have defined functionally important roles in mammalian tissue repair. Although recent evidence suggests that similar cells exist in zebrafish and also migrate to sites of injury in larvae, whether these cells are functionally important for wound healing or regeneration in adult zebrafish is unknown. To begin to address these questio...

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ژورنال

عنوان ژورنال: Scientific Reports

سال: 2015

ISSN: 2045-2322

DOI: 10.1038/srep11428